Posters

Bridging the gap between venom research and modern drug discovery

Steven A Trim

GRC- Venom Evolution, Function and Biomedical Applications

Purified Venom Components Inhibit EGFR Phosphorylation in Triple Negative Breast Cancer

Danielle McCullough, Stuart Baker, Steven A Trim, Carol Trim

EACR 2022

Development of robust, transferable, high throughput cell viability assays to discover venom peptides with selective activity against cancer cells

Steven A Trim, Emily Knight, Alice Upton, Danielle McCullough, Charlotte Akers, Carol Trim

SLAS Europe 2022

Examining the synergistic effect of venoms to enhance chemotherapeutics and irradiation using high content cell imaging

Steven A Trim, Rod Benson and Gareth Griffiths

SLAS Europe 2022

Novel biologics for disrupting programmed cell death receptor PD-1 binding to PD-L1

Steven A Trim, Danielle McCullough, Stuart Baker and Paul Grant

Novel GPCR Ligands: GPR120 Case Study

Danielle McCullough, Steven A Trim, Stuart Baker and Paul Grant

Identifying novel and selective sodium channel modulators from Theraphosidae venoms

Elaine M Duncan, Danielle McCullough, Stephen Grace, Stuart Baker, Juha Kammonen, Paul Grant, Steven A Trim & Vad Lazari1

Safe laboratory management for true spiders (Araneomorphae) of medical importance

Reed, S.E., Lock, M.M.G & Trim, S.A.
LASA winter meeting 2010

Characterisation of Novel African Diplopod Defensive Fluids

Trim, C.M. & Trim, S.A.
International Society of Toxicology European Meeting, 2011

Novel haemoglobin modifying activity discovered through screening T-VDACV

Hayter, P., Datwani, S., Ellson, R., Croucher, L., Wark, C., Baines, A., & Trim, S.A.
ELRIG Drug Discovery 2013

Targeting Breast Cancer Signalling Pathways with Animal Venoms

McCullough, D., Atofanei, C., Knight, E., Trim, S.A. & Trim, C.M.
ELRIG Drug Discovery 2016

The antimicrobial effects of animal venom

Wyles, J., Bendo, M., Hale, G., Holmes, H., Trim, S.A. & Trim, C.M.
ELRIG Drug Discovery 2016

Evaluation of venoms as a source of novel ligands for drug discovery

Plant, H., Stacey, C., Wigglesworh, M., & Sinclair, I.
ELRIG Drug Discovery 2016

Identification of Cobra Venom Actives as Potential Novel Pancreatic Cancer Therapeutics

Knight, E.L., Trim, S.A. & Trim, C.M.
Cambridge Pancreatic Cancer Symposium 2017

Activating challenging GPCRs with venom peptides

Williamson, H.K., Bennett, N. & Walsh, J.
ELRIG Drug Discovery 2017

Improving GFP production utilising venom components to enhance transfection efficiency in Cos 7 cells

Roznovcova, M., Trim, S.A. & Trim, C.M.
Canterbury Christ Church University Symposium 2018

Naja nigricollis Venom Exosomes Biological Functions and Interactions

Lundin, A., Trim, S.A., Trim, C.M. & Wilson, C.
Canterbury Christ Church University Symposium 2018

Investigation of the antibacterial activity of venoms against Staphylococcus aureus

Hegerova, L., Trim, S.A. & Byrne, L.
Canterbury Christ Church University Symposium 2018

Investigating the effects of Naja nigricollis venom on colorectal and pancreatic cancer cell lines

Farooq, I., Trim, S.A., Knight, E.L. & Trim, C.M.
Canterbury Christ Church University Symposium 2018

Identification of novel scorpion venom peptide inhibitors of the Kv1.3 ion channel and their potential as drug discovery leads for human T-cell mediated disease

Kirby, R.W., Tang, R., Witton, I., Webdale, L., Baker, S., Knight, E., Trim, S.A. & Rogers, R.
ELRIG Drug Discovery 2018

Identification of novel scorpion venom peptide inhibitors of the Kv1.3 ion channel and their potential as drug discovery leads for human T-cell mediated disease

Kirby, R.W., Tang, R., Witton, I., Webdale, L., Baker, S., Knight, E., Trim, S.A. & Rogers, R.
ELRIG Drug Discovery 2018

Development of a Compound Library from Cobra Venom and the Results of Cytotoxicity Screening in SW620 Colorectal Cancer Cells

Knight, E., Trim, S.A & Trim, C.
ELRIG Drug Discovery 2018

Investigation of a Panel of Snake Venoms for EGFR Phosphorylation Reducing Capabilities in EGFR Over-Expressing Cancers

McCullough, D., Trim, S.A & Trim, C.
ELRIG Drug Discovery 2018

Microprotein Hit Finding Library Uncovers Bee Venom PLA2 Inhibited by Spider Venom

Knight, E. & Trim, S.A
ELRIG Drug Discovery 2019

Spider vs Snake – discovery of novel snake venom protease inhibitors from spider venom

Destriau, R., McCullough, D., Rowlinson, R., Abbott, W.M. & Trim, S.A.
ELRIG Drug Discovery 2019