Venom A to Z- J is for Juruin

Venom A to Z- J is for Juruin an antifungal peptide from the pink toed tarantula Avicularia juruensis. Also called Juruentoxins These peptides are small (3.5 – 4.5KDa) cystine knot peptides like the typical neurotoxins from theraphosids. 11 have been found so far and they provide a useful insight into the mechanisms of fungal death and a useful template for improvements. These sorts of structural activity relationships (SAR) form part of our hit to lead follow-up service.

Pictured below is another pinktoe species avicularia Metallica which is closely related.