DRUG DISCOVERY SOLUTIONS

Hit-to-Lead Services

Unlock the full potential of the Targeted Venom Discovery Arrays™ (T-VDAs) with this custom hit characterisation and lead optimisation service. The Venomtech team have decades of experience in global pharmaceutical drug discovery coupled with specialist knowledge of venoms and venomous animals. Using our industry-leading proprietary safe working practices we turn millions of years of evolution into the ultimate drug discovery pipeline. This starts with the T-VDA already optimised to provide biological tools in areas where synthetic chemistry has failed or where a biological is specifically sought.

1. Full identification of active component(s)

  • Characterisation of active fraction(s)
    • LC-MS, MALDI-TOF, MS/MS
  • Purification of single active(s)
    • For libraries not fully pre-fractionated
  • Resupply of actives for dose response testing
    • Milligram quantities purified from original venoms
  • Small scale synthesis of the pure active
    • Up to grams, either synthetic (<150 amino acids) or cloned for larger proteins
  • Large (up to 1kg) synthetic production (<150 amino acids), at GMP grade if needed, of single peptides

2. Hit-to-lead development

  • Provision of closely related targeted venoms to enhance potency and/or selectivity
  • Determination of structure-activity relationship (SAR)
  • Modifications for improved stability, delivery, bioavailability, etc
  • Toxicity testing, proof of concept and proof of mechanism in standard models

Available products for cosmetics and drug discovery

Anti-inflammitory cosmetic venom skin

Anti-inflammatory 

Cosmetic peptides to soothe skin and reduce inflammation

Antipollution skin toxins venom

Antipollution 

Cosmetic peptides to protect skin from toxins and pollutants

Venom peptides

VenomSELECTTM 

Our bespoke cosmetic peptide design service

drug target drug discovery venom

Target-based 

Target-based venom arrays for hard-to-hit drug targets

Therapeutic cancer research venom

Therapeutic areas 

Venom arrays for antimicrobial, pain, cancer research, etc.

Venom research target array

Custom Arrays 

Venom arrays designed by us for your target or research area

Resources: Supporting material to aid your research

Science Exchange

Do business via the world's leading and most secure R&D outsourcing platform

Papers and Posters venom

Papers & Posters

Helpful publications from our team, our partners and key industry sources

News and events venom

News & Media

Up-to-date events and news items about the species, the science and our team

People and partners venom

FAQs

Find  answers to your most frequently asked questions regarding our products