DRUG DISCOVERY SOLUTIONS

Venom Publications

Venomtech Scientific Posters

Investigation of a Panel of Snake Venoms for EGFR Phosphorylation Reducing Capabilities in EGFR Over-Expressing Cancers

McCullough, D., Trim, S. & Trim, C.

ELRIG Drug Discovery 2018

 

 Development of a Compound Library from Cobra Venom and the Results of Cytotoxicity Screening in SW620 Colorectal Cancer Cells

Knight, E., Trim, S. & Trim, C.

ELRIG Drug Discovery 2018

 

Identification of novel scorpion venom peptide inhibitors of the Kv1.3 ion channel and their potential as drug discovery leads for human T-cell mediated disease

Kirby, R.W., Tang, R., Witton, I., Webdale, L., Baker, S, Knight, E., Trim, S.A. & Rogers, R.

ELRIG Drug Discovery 2018

 

Investigating the effects of Naja nigricollis venom on colorectal and pancreatic cancer cell lines 

Farooq, I.,  Trim, S.A.,  Knight, E.L. & Trim, C.M

Canterbury Christ Church University Symposium 2018

 

 Investigation of the antibacterial activity of venoms against Staphylococcus aureus

Hegerova, L., Trim, S.A. & Byrne, L.

Canterbury Christ Church University Symposium 2018

 

 Naja nigricollis Venom Exosomes Biological Functions and Interactions

Lundin, A., Trim, S.A., Trim, C.M & Wilson, C.

Canterbury Christ Church University Symposium 2018

 

 Improving GFP production utilising venom components to enhance transfection efficiency in Cos 7 cells

Roznovcova, M., Trim, S.A. & Trim, C.M.

Canterbury Christ Church University Symposium 2018

 

 Activating challenging GPCRs with venom peptides

Williamson, H.K, Bennett, N. & Walsh, J.

ELRIG Drug Discovery 2017

 

  Identification of Cobra Venom Actives as Potential Novel Pancreatic Cancer Therapeutics

Knight, E.L., Trim, S.A. & Trim, C.M.

Cambridge Pancreatic Cancer Symposium 2017

 

 Evaluation of venoms as a source of novel ligands for drug discovery

Plant, H., Stacey, C., Wigglesworh, M., & Sinclair, I.

ELRIG Drug Discovery 2016

 

The antimicrobial effects of animal venom

Wyles, J., Bendo, M., Hale, G., Holmes, H., Trim, S.A. & Trim, C.M.

ELRIG Drug Discovery 2016

 

 Targeting Breast Cancer Signalling Pathways with Animal Venoms

McCullough, D., Atofanei, C., Knight, E., Trim, S.A. & Trim, C.M.

ELRIG Drug Discovery 2016

 

 Novel haemoglobin modifying activity discovered through screening T-VDACV

Hayter, P., Datwani, S., Ellson, R., Croucher, L., Wark, C., Baines, A., & Trim, S.A.

ELRIG Drug Discovery 2013

 

 Characterisation of Novel African Diplopod Defensive Fluids

Trim, C.M & Trim, S.A.

International Society of Toxinology European Meeting, 2011

 

Safe laboratory management for true spiders (Araneomorphae) of medical importance

Reed, S.E., Lock, M.M.G & Trim, S.A.

LASA winter meeting 2010

 

Venomtech Scientific Papers

Tarantula husbandry and critical care

Pellett, S., Bushell, M and Trim, S.A (2015)

Companion Animal. 20 (2)

 

 Venom: the sharp end of pain therapeutics

Trim, S.A and Trim, C.M (2013)

British Journal of Pain. 7 (4)

 

 Refining laboratory husbandry of venomous snakes of the family Elapidae

Loaring, C and Trim, S.A.

Animal Technology and Welfare, December 2012

 

Laboratory husbandry of arboreal tarantulas (Theraphosidae) and evaluation of environmental enrichment

Bennie, M.G., Loaring, C. and Trim, S.A.

Animal Technology and Welfare, December 2011

 

Safe laboratory management for arachnids of medical importance

Reed, S.E., Lock, M.G and Trim, S.A.

Animal Technology and Welfare, August 2011

 

Venomtech White Papers

Venom Reviews and Scientific Papers

Chassagnon, I.R., McCarthy, C.A., Chin, Y.K.-Y., Pineda, S.S., Keramidas, A., Mobli, M., Pham, V., De Silva, T.M., Lynch, J.W., Widdop, R.E., Rash, L.D. & King, G.F. (2017). Proceedings of the National Academy of Sciences of the United States of America 114: 143750-3755.

 

Osteen, J.D., Herzig, V., Gilchrist, J., J. Emrick, J.J., Zhang, C., Wang, X., Castro, J., Garcia-Caraballo, S., Grundy, L., Rychkov, G.Y, Weyer, A.D., Dekan, Z., Undheim, E.A.B., Alewood, P., Stucky, C.L., Brierley, S.M., Basbaum, A.I., Bosmans, F., King, G.F. & Julius, D. (2016).  Nature 534: 494–499

 

Fosgerau, K and Hoffmann, T. (2015).  Drug Discovery Today 20 (1):122-128.

 

Hardy, M.C., Daly, N.L., Mobli, M., Morales, R.A.V. & King, G.F. (2013). PLoS ONE, 8 (9)

 

Quintero-Hernández, V., Jiménez-Vargas, J.M., Gurrola, G.B., Valdivia, H.H. & Possani, L.D. (2013).  Toxicon 76: 328-342

 

Diochot, S., Baron, A., Salinas, M., Douguet, D., Scarzello, S., Dabert-Gay, A.S., Debayle, D., Friend, V., Alloui, A., Lazdunski, M., Lingueglia, E. (2012). Nature, 490 (7421)

 

Dutertre, S. and Lewis, R.J. (2010).  Journal of Biological Chemistry 285: 13315-13320.

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Papers and posters venom

Papers & Posters

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News & Media

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