Venom Publications
Venomtech Scientific Posters
Investigation of a Panel of Snake Venoms for EGFR Phosphorylation Reducing Capabilities in EGFR Over-Expressing Cancers
McCullough, D., Trim, S. & Trim, C.
ELRIG Drug Discovery 2018
Development of a Compound Library from Cobra Venom and the Results of Cytotoxicity Screening in SW620 Colorectal Cancer Cells
Knight, E., Trim, S. & Trim, C.
ELRIG Drug Discovery 2018
Identification of novel scorpion venom peptide inhibitors of the Kv1.3 ion channel and their potential as drug discovery leads for human T-cell mediated disease
Kirby, R.W., Tang, R., Witton, I., Webdale, L., Baker, S., Knight, E., Trim, S.A. & Rogers, R.
ELRIG Drug Discovery 2018
Investigating the effects of Naja nigricollis venom on colorectal and pancreatic cancer cell lines
Farooq, I., Trim, S.A., Knight, E.L. & Trim, C.M.
Canterbury Christ Church University Symposium 2018
Investigation of the antibacterial activity of venoms against Staphylococcus aureus
Hegerova, L., Trim, S.A. & Byrne, L.
Canterbury Christ Church University Symposium 2018
Naja nigricollis Venom Exosomes Biological Functions and Interactions
Lundin, A., Trim, S.A., Trim, C.M. & Wilson, C.
Canterbury Christ Church University Symposium 2018
Improving GFP production utilising venom components to enhance transfection efficiency in Cos 7 cells
Roznovcova, M., Trim, S.A. & Trim, C.M.
Canterbury Christ Church University Symposium 2018
Activating challenging GPCRs with venom peptides
Williamson, H.K., Bennett, N. & Walsh, J.
ELRIG Drug Discovery 2017
Identification of Cobra Venom Actives as Potential Novel Pancreatic Cancer Therapeutics
Knight, E.L., Trim, S.A. & Trim, C.M.
Cambridge Pancreatic Cancer Symposium 2017
Evaluation of venoms as a source of novel ligands for drug discovery
Plant, H., Stacey, C., Wigglesworh, M., & Sinclair, I.
ELRIG Drug Discovery 2016
The antimicrobial effects of animal venom
Wyles, J., Bendo, M., Hale, G., Holmes, H., Trim, S.A. & Trim, C.M.
ELRIG Drug Discovery 2016
Targeting Breast Cancer Signalling Pathways with Animal Venoms
McCullough, D., Atofanei, C., Knight, E., Trim, S.A. & Trim, C.M.
ELRIG Drug Discovery 2016
Novel haemoglobin modifying activity discovered through screening T-VDACV
Hayter, P., Datwani, S., Ellson, R., Croucher, L., Wark, C., Baines, A., & Trim, S.A.
ELRIG Drug Discovery 2013
Characterisation of Novel African Diplopod Defensive Fluids
Trim, C.M. & Trim, S.A.
International Society of Toxinology European Meeting, 2011
Safe laboratory management for true spiders (Araneomorphae) of medical importance
Reed, S.E., Lock, M.M.G & Trim, S.A.
LASA winter meeting 2010
Venomtech Scientific Papers
Impact of Naja nigricollis Venom on the Production of Methaemoglobin
Williams, H.F., Hayter, P., Ravishankar, D., Baines, A., Layfield, H.J., Croucher, L., Wark, C., Bicknell, A.B., Trim, S., & Vaiyapuri, S. (2018)
Toxins. 10 (12)
Tarantula husbandry and critical care
Pellett, S., Bushell, M. and Trim, S.A. (2015)
Companion Animal. 20 (2)
Venom: the sharp end of pain therapeutics
Trim, S.A. and Trim, C.M. (2013)
British Journal of Pain. 7 (4)
Refining laboratory husbandry of venomous snakes of the family Elapidae
Loaring, C. and Trim, S.A.
Animal Technology and Welfare, December 2012
Laboratory husbandry of arboreal tarantulas (Theraphosidae) and evaluation of environmental enrichment
Bennie, M.G., Loaring, C. and Trim, S.A.
Animal Technology and Welfare, December 2011
Safe laboratory management for arachnids of medical importance
Reed, S.E., Lock, M.G. and Trim, S.A.
Animal Technology and Welfare, August 2011
Venomtech White Papers
Identification of novel haemoglobin-modifying activity in snake venom libraries using the PHERAstar FS
Hayter, P., Croucher, L., Wark, C., Baines, A., and Trim, S.A.
Venom Reviews and Scientific Papers
- A New Topical Eye Drop Containing LyeTxI-b, a Synthetic Peptide Designed from a Lycosa erithrognata Venom Toxin, Was Effective to Treat Resistant Bacterial Keratitis.
Silva C.N.D., Silva F.R.D., Dourado L.F.N., Reis P.V.M.D., Silva R.O., Costa B.L.D., Nunes P.S., Amaral F.A., Santos V.L.D., de Lima M.E. & Silva Cunha Júnior A.D. (2019) Toxins (Basel). 11 (4)Peptidomic characterization and bioactivity of Protoiurus kraepelini (Scorpiones: Iuridae) venom.
Somay Doğan T., Iğci N., Biber A., Gerekçi S., Hüsnügil H.H., Izbirak A. & Özen C. (2018) Turk J Biol. 42: 490-497. - Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a.
Chassagnon, I.R., McCarthy, C.A., Chin, Y.K.-Y., Pineda, S.S., Keramidas, A., Mobli, M., Pham, V., De Silva, T.M., Lynch, J.W., Widdop, R.E., Rash, L.D. & King, G.F. (2017). Proceedings of the National Academy of Sciences of the United States of America 114: 143750-3755.
- Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain.
Osteen, J.D., Herzig, V., Gilchrist, J., J. Emrick, J.J., Zhang, C., Wang, X., Castro, J., Garcia-Caraballo, S., Grundy, L., Rychkov, G.Y, Weyer, A.D., Dekan, Z., Undheim, E.A.B., Alewood, P., Stucky, C.L., Brierley, S.M., Basbaum, A.I., Bosmans, F., King, G.F. & Julius, D. (2016). Nature 534: 494–499
- Peptide therapeutics: current status and future directions.
Fosgerau, K. and Hoffmann, T. (2015). Drug Discovery Today 20 (1):122-128.
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Isolation of an Orally Active Insecticidal Toxin from the Venom of an Australian Tarantula
Hardy, M.C., Daly, N.L., Mobli, M., Morales, R.A.V. & King, G.F. (2013). PLoS ONE, 8 (9)
- Scorpion venom components that affect ion-channels function.
Quintero-Hernández, V., Jiménez-Vargas, J.M., Gurrola, G.B., Valdivia, H.H. & Possani, L.D. (2013). Toxicon 76: 328-342
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Black mamba venom peptides target acid-sensing ion channels to abolish pain
Diochot, S., Baron, A., Salinas, M., Douguet, D., Scarzello, S., Dabert-Gay, A.S., Debayle, D., Friend, V., Alloui, A., Lazdunski, M., Lingueglia, E. (2012). Nature, 490 (7421)
- Use of Venom Peptides to Probe Ion Channel Structure and Function.
Dutertre, S. and Lewis, R.J. (2010). Journal of Biological Chemistry 285: 13315-13320.
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