Are venom peptides immunogenic?
Venom peptides used in drug discovery, cosmetics and crop science are poorly recognised by the immune systems of animals. They rarely illicit an immune response, even when one is needed. Many venom components, especially small peptides, are poorly immunogenic. Whole snake venoms do elicit immune reactions, including anaphylaxis, in humans. Due to of the risk of whole venom sensitisation, we operate strict, safe systems of work, including local exhaust ventilation to protect our staff.