Diversity Set

For some projects or targets there are no known venom leads and thus a targeted approach is too risky. In such circumstances where a biochemical (cell free) assay is available, crude whole venom can be used, as these assays are less sensitive to off-target effects. Each venom contains several hundred different components and therefore deconvolution takes longer, but still delivers useful tools for novel targets.


30 crude whole venoms in triplicate, from a phylogenetically and geographically diverse set of species, selected to maximise hit potential on novel targets. 10 mg/well. As there is no common venomous ancestor between snakes, scorpions, spiders and centipedes the diversity of molecular classes is large. The diversity continues within groups as there are species origination from across the globe and from different habitats, which all power natural selection in different ways. The diversity set is often used as a pre-screen to then design a Targeted – Venom Discovery Array™ (T-VDA™) with fractionated venoms, to find closely related hit molecules for potential Structural Activity Relationship (SAR) studies

Example Plate layout

Full species list

Code Species Group Family/sub-family
S.har Scolopendra hardwickei Centipede Scolopendridae
A.aus Androctonus australis Scorpion Buthidae
P.lio Parabuthus liosoma Scorpion Buthidae
H.ari Hadrurus arizonensis Scorpion Caraboctonidae
H.pau Hadogenes paucidens Scorpion Hemiscorpiidae
P.kra Protoiurus Kraepelini Scorpion Iuridae
H.swa Heterometrus swammerdami Scorpion Scorpionidae
O.scc Oxyuranus scutellatus canni Snake (taipan) Elapinae
N.mel Naja melanoleuca Snake (cobra) Elapinae
N.nig Naja nigricollis Snake (cobra) Elapinae
N.sia Naja siamensis Snake (cobra) Elapinae
D.pol Dendroaspis polylepis Snake (mamba) Elapinae
D.ang Dendroaspis angusticeps Snake (mamba) Elapinae
C.rho Calloselasma rhodostoma Snake (pit viper) Crotalinae
C.atr Crotalus atrox Snake (pit viper) Crotalinae
C.rru Crotalus ruber Snake (pit viper) Crotalinae
S.mil Sistrurus miliarius barbouri Snake (pit viper) Crotalinae
T.vog Trimeresurus vogeli Snake (pit viper) Crotalinae
M.xan Montivipera xanthina Snake (viper) Viperinae
B.grh Bitis gabonica rhinoceros Snake (viper) Viperinae
A.met Avicularia metallica Theraphosid Aviculariinae
T.cup Tapinauchenius cupreus Theraphosid Aviculariinae
E.pac Eucratoscelus pachypus Theraphosid Eumenophorinae
P.lug Pterinochilus lugardi Theraphosid Harpactirinae
H.lbo Cyriopagopus albostriatum Theraphosid Ornithoctoninae
P.for Poecilotheria formosa Theraphosid Poecilotheriinae
P.cam Psalmopoeus cambridgei Theraphosid Selenocosmiinae
H.mac Heteroscodra maculata Theraphosid Stromatopelminae
A.cor Acanthoscurria cordubensis Theraphosid Theraphosinae
T.str Theraphosa stirmi Theraphosid Theraphosinae

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