DRUG DISCOVERY SOLUTIONS

Diverse Crude Venom Array

Diverse crude venom arrayA diverse crude venom array for those projects or targets where there are no known venom leads and where a targeted approach is too risky. Crude venom can be used in circumstances where a biochemical (cell free) assay is available, as these assays are less sensitive to off-target effects. Each venom contains several hundred different components and therefore deconvolution takes longer, but still delivers useful tools for novel targets.

Description

30 crude venom in triplicate, from a phylogenetically and geographically diverse set of species, selected to maximise hit potential on novel targets. As there is no common venomous ancestor between snakes, scorpions, spiders and centipedes, the diversity of molecular classes is large. The diversity continues within groups because we include species that originate from across the globe and from different habitats, both of which power natural selection in different ways. The diversity set is often used as a pre-screen to inform the design of a Targeted – Venom Discovery Array™ (T-VDA™) using fractionated venoms, and subsequently, to find closely related hits for potential Structural Activity Relationship (SAR) studies.

Example Plate layout (1 mg/well)

Full Crude Venom Array Species List

Code Species Group Family/sub-family
S.har Scolopendra hardwickei Centipede Scolopendridae
A.aus Androctonus australis Scorpion Buthidae
P.lio Parabuthus liosoma Scorpion Buthidae
H.ari Hadrurus arizonensis Scorpion Caraboctonidae
H.pau Hadogenes paucidens Scorpion Hemiscorpiidae
P.kra Protoiurus Kraepelini Scorpion Iuridae
H.swa Heterometrus swammerdami Scorpion Scorpionidae
O.scc Oxyuranus scutellatus canni Snake (taipan) Elapinae
N.mel Naja melanoleuca Snake (cobra) Elapinae
N.nig Naja nigricollis Snake (cobra) Elapinae
N.sia Naja siamensis Snake (cobra) Elapinae
D.pol Dendroaspis polylepis Snake (mamba) Elapinae
D.ang Dendroaspis angusticeps Snake (mamba) Elapinae
C.rho Calloselasma rhodostoma Snake (pit viper) Crotalinae
C.atr Crotalus atrox Snake (pit viper) Crotalinae
C.rru Crotalus ruber Snake (pit viper) Crotalinae
S.mil Sistrurus miliarius barbouri Snake (pit viper) Crotalinae
T.vog Trimeresurus vogeli Snake (pit viper) Crotalinae
M.xan Montivipera xanthina Snake (viper) Viperinae
B.grh Bitis gabonica rhinoceros Snake (viper) Viperinae
A.met Avicularia metallica Theraphosid Aviculariinae
T.cup Tapinauchenius cupreus Theraphosid Aviculariinae
E.pac Eucratoscelus pachypus Theraphosid Eumenophorinae
P.lug Pterinochilus lugardi Theraphosid Harpactirinae
H.lbo Cyriopagopus albostriatum Theraphosid Ornithoctoninae
P.for Poecilotheria formosa Theraphosid Poecilotheriinae
P.cam Psalmopoeus cambridgei Theraphosid Selenocosmiinae
H.mac Heteroscodra maculata Theraphosid Stromatopelminae
A.cor Acanthoscurria cordubensis Theraphosid Theraphosinae
T.str Theraphosa stirmi Theraphosid Theraphosinae

Available products for cosmetics and drug discovery

Cosmetic peptides anti-inflammatory

Anti-inflammatory 

Cosmetic peptides to soothe skin and reduce inflammation

Antipollution skin toxins

Antipollution 

Cosmetic peptides to protect skin from toxins and pollutants

Venom cosmetic peptide

VenomSELECTTM 

Our bespoke cosmetic peptide design service

Drug discoery targets venom

Target-based 

Target-based venom arrays for hard-to-hit drug targets

Therapeutic cancer research venom

Therapeutic areas 

Venom arrays for antimicrobial, pain, cancer research, etc.

Venom array drug discovery research

Custom Arrays 

Venom arrays designed by us for your target or research area

Resources: Supporting materials to aid your research

Papers and posters venom

Papers & Posters

Helpful publications from our team, our partners and key industry sources

News and events venom

News & Media

Up-to-date events and news items about the species, the science and our team

People and partners venom

FAQs

Find answers to your most frequently asked questions regarding our products